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Additionally, exercise is an important tool recommended by the ADA guidelines to prevent and treat obesity in diabetes mellitus patients (104) and can improve patients blood glucose levels and insulin resistance (105)

Therefore, melasma treatment, especially in patients with dark skin types classified as Fitzpatrick types IV to VI, is challenging due to the possibility of relapse and also susceptibility to post-inflammatory hyperpigmentation (PIH) (Rodrigues and Pandya, 2015)

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Clinical injectable BPC-157 from a licensed US compounding pharmacy is not the same compound as unregulated OTC powders sold online