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Medical Consensus: High Serum B12 in Supplementers is Safe The medical community broadly agrees that high serum B12 levels resulting from supplementation are safe for individuals with no underlying health issues

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Agmatine co-transmission in addiction Given reports of Glu/Agm co-transmission, and Agms dual roles as an extracellular antagonist of NMDA receptors (Figure 2) and an intracellular antagonist of NOS, it is reasonable to hypothesize that Agm may interact with the NMDA-NOS axis involved in addiction-driven learning experienced during withdrawal (Uzbay, 2012)