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Severe kidney impairment : Individuals with severe kidney disease or renal insufficiency are at higher risk of developing further renal complications with semaglutide use

It contains the same active ingredient as the Wegovy injection and as Rybelsus (the lower-dose oral semaglutide licensed for type 2 diabetes), but at a higher strength approved specifically for weight management

doi: 10.1152/ajpendo.00465.2005

The most common side effects of Ozempic affect more than 1 in 10 people and are gastrointestinal, including nausea, vomiting, diarrhoea, abdominal pain, and constipation