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Metabolic Health: It may affect blood sugar levels, which may be relevant for individuals with certain metabolic conditions

However, human clinical trials demonstrating sustained tissue accumulation and functional antioxidant benefit remain sparse, making real-world efficacy difficult to quantify

Although the effect of gut-derived GLP-1 at physiologic concentrations on energy balance seems to be mediated by action on peripheral vagal afferents, recently developed GLP-1RAs appear to have significant weight-loss effects predominantly through direct central activation of GLP-1Rs

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