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Sansone is a family medicine physician (civilian) and Medical Director, Family Health Clinical, Wright-Patterson Medical Center in WPAFB, Ohio

This dual mechanism is essential for enhancing metabolic health by increasing insulin secretion in response to elevated blood glucose levels while simultaneously suppressing the excessive release of glucagon

We demonstrate that rSP1 induces endothelial inflammation via ACE2 through processes that are independent of ACE2 enzymatic activity and viral replication