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BMJ 341:c2701 Manfield JH et al (2017) Bariatric surgery or non-surgical weight loss for idiopathic intracranial hypertension

In the SURMOUNT 1 trial, tirzepatide 15 mg/wk with general nutritional instructions produced a 20.9 % reduction in body weight from baseline (versus 3.1 % with general nutrition instructions alone) [15], whereas in the SURMOUNT 3 trial, tirzepatide 10 or 15 mg/wk started after 12 weeks of intensive lifestyle intervention produced a 25 % reduction from baseline (versus 4.8 % with intensive lifestyle intervention alone) [170]

He's a professor at the Department of Biomedical Sciences at the University of Copenhagen in Denmark, and he's won several of the world's most prestigious awards in science, including the 2020 Warren Alpert Foundation Prize and the 2021 Canada Gairdner International Awards and the 2025 Breakthrough Prize in Life Sciences, and he shared the Alpert Prize, by the way, with other scientists in the United States as well

Naltrexone is an opioid antagonist, meaning it blocks the effects of opioids and can trigger sudden, severe withdrawal symptoms in people who are physically dependent on them