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Introduction Liver dysfunction leads to metabolic disorders and ultimately endangers personal health ( NAFLD is a chronic progressive lesion involving in inflammation, oxidative stress, insulin resistance, and imbalances in lipid metabolism ( Several studies have demonstrated that ferroptosis plays a crucial role in the occurrence of NAFLD ( Ferroptosis and non-alcoholic fatty liver disease/non-alcoholic fatty liver disease-hepatocellular carcinoma Ferroptosis Ferroptosis is a non-apoptosis with a completely different morphology