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Vitamin B6 is added to semaglutide to possibly reduce gastrointestinal side effects, which may make it less likely for patients to skip doses or discontinue treatment

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Brand-Specific Storage Guidelines Mounjaro & Zepbound (Tirzepatide) Store in refrigerator Can remain at room temperature for up to 21 days Do not return to refrigerator once left out Ozempic (Semaglutide) Refrigerate before first use After opening, store in fridge or at room temperature for up to 56 days Wegovy (Semaglutide) Store in refrigerator Can remain at room temperature for up to 28 days Compounded Semaglutide / Tirzepatide Keep refrigerated at all times Follow pharmacy-specific instructions How to Travel with GLP-1 Medications in Florida Travel is one of the most common reasons medications are stored incorrectly

PLoS ONE 8 , e69010 (2013)