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For broader context, MOTS-c belongs to the same family of mitochondrial peptides as Humanin, another MDP being studied for its protective role in aging and cellular stress

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Peterson RJ, Marsh CL: The relationship of alpha1-antitrypsin to inflammatory periodontal disease

We identified key regions in the p53 transactivation domain (TAD) involved in FOXO4 binding and designed an optimized peptide inhibitor (CPP-CAND) with improved cell permeability