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Specific recommendations often include magnesium-rich foods (e.g., leafy greens, nuts) to help manage cortisol levels, omega-3 fatty acids for their anti-inflammatory effects and brain health benefits, and probiotic-rich foods to enhance gut health, which is often compromised by stress

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Notably, HIF-2, another key HIF family member also regulated by hypoxia and sharing some target genes, may exhibit distinct roles from HIF-1 in ROS regulation, sometimes even promoting ROS generation under specific conditions, highlighting the nuanced complexity of this family in ROS homeostasis [136]

In West African countries (460) and Brazil (461)