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Consequently, researchers observe a significantly extended half-life (estimated between 20 to 30 hours) and substantially increased biological potency in vitro

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References Novo Nordisk presents phase 3 data for next-generation amylin cagrilintide, leading to advancement into dedicated clinical Programme, 16 September 2025, Novo Nordisk, DAscanio AM, Mullally JA, Frishman WH