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During this time, hormonal fluctuations become dramatic and can cause physical and mental changes in women

Hence, it can interfere with the endocrine system, leading to adverse health outcomes and effects on male reproductive axis causing infertility (78)

After 48 h, biofilms were washed once with 1 PBS followed by treatment with different enzyme solutions prepared in 1 PBS, pH 7.4, including: 5, 10, 20, and 40U DNase-I, 100, 200, 500 and 1000 g/ml amylase and 50, 100, 200 and 500 g/ml Proteinase K, for 24 h, at 37C and 150 rpm, the control was treated with 1 PBS alone

Galactose-modified PH-Sensitive niosomes for controlled release and hepatocellular carcinoma target delivery of tanshinone IIA