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The case scenarios illustrate that sometimes taking a woman off an offending medication is just as effective as prescribing a medication to relieve HSDD symptoms

FDA-approved peptides like semaglutide and tirzepatide may be covered when prescribed for approved indications (diabetes, obesity), but compounded peptides, off-label uses, and anti-aging applications are typically out-of-pocket expenses

The researchers also conducted RNA-sequencing, which apparently pointed to reduced activity of pathways involved in ECMreceptor interaction and focal adhesion, alongside lower levels of key ECM proteins such as fibronectin, tenascin C, laminin, thrombospondin-2, and Hmmr

Accepted for publication January 20, 2025