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However, some patients may experience persistent fatigue, which warrants further clinical evaluation to exclude other contributing factors such as nutritional deficiencies (particularly iron, vitamin B12, or vitamin D), thyroid dysfunction, or inadequate protein intake

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GLP-1 agonists is currently approved as second/third-line therapy for T2DM patients with inadequate glycaemic control (HbA1c 7.0 or 53 mmol/mol) despite lifestyle modifications and first-line antihyperglycaemics (metformin/sulfonylurea/insulin)

Cell lines were generated as indicated and each condition was collected in triplicates of 1,000,000 cells each