optavia and semaglutide A lot of people ask me how compares to GLP-1 medications. Here's my take… I'm not anti-GLP-1. I'm anti watching people lose weight lose muscle, energy, and healthy habits right Weight-Loss Drug Semaglutide Making People

Commonly reported side effects include: nausea vomiting diarrhoea constipation abdominal pain indigestion bloating headache fatigue dizziness These symptoms may improve as the body adjusts to treatment

And the two are not always mutually exclusive

for instance, it may increase serum levels of markers like inorganic phosphorus or alkaline phosphatase

In the landmark STEP 1 trial (Once-Weekly Semaglutide in Adults with Overweight or Obesity, Wilding and colleagues, New England Journal of Medicine , 2021), 1,961 adults who took weekly semaglutide (2.4 mg) plus lifestyle support lost a mean of 14.9% of their body weight over 68 weeks, compared with 2.4% on placebo, and 86% achieved at least 5% weight loss