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We observed that more than one-third of metabolites detected in heart were significantly altered with aging, which was predominantly characterized by a rise in the level of glycerophospholids, and to a lesser extent, acylcarnitines (Fig

Both Enterobacter aerogenes ZDY01 and Lactobacillus plantarum ZDY04 can reduce TMAO levels, showing that the positive effects of them on the heart may be partially realized by reducing TMAO levels [73,74]

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