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Healthcare professionals can assess hydration status, perform relevant investigations (such as stool cultures if indicated), and determine whether hospital admission for intravenous fluids or further management is necessary

Tolcapone, an inhibitor of COMT (catechol- O-methyltransferase, the enzyme which normally inactivates dopamine), became available in 1998

Even with steady progress, some areas may look loose because the supporting structures beneath the skin have changed, and some people report facial skin that appears more aged after weight loss