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MHRA-licensed options available in the UK include orlistat (Xenical or Alli), semaglutide (Wegovy), and liraglutide (Saxenda), all recommended by NICE under specific clinical criteria and used alongside dietary and lifestyle changes

Personalized programs often include guidance on how to navigate these challenges

"Today's approval offers adults with obesity or overweight a beneficial new treatment option to incorporate into a weight management program," said John Sharretts, M.D., deputy director of the Division of Diabetes, Lipid Disorders, and Obesity in the FDA's Center for Drug Evaluation and Research in a statement

10.1016/j.ccell.2015.01.009 24 HuH.XuQ.MoZ.HuX.HeQ.ZhangZ.et al (2022)