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Second, the employer-facing expansion of Cost Plus, particularly through the CenterWell/Humana partnership announced in April 2026, is changing plan sponsor expectations about drug pricing in ways that affect formulary negotiations for in-patent drugs today

The REWIND trial with dulaglutide included many patients without established ASCVD and demonstrated a consistent reduction in MACE, supporting a role in primary prevention, although the effect size was modest

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Patients who carry variants associated with rapid satiety onset often report that evening injections prevent excessive daytime appetite suppression, maintaining normal work-day nutrition