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The primary objective of this meta-analysis was the comparison of the time to first occurrence of confirmed four-component major adverse cardiovascular events including cardiovascular death, myocardial infarction, stroke and hospitalized unstable angina between tirzepatide groups and control groups

These include: dizziness difficulty sleeping dry mouth irritability Less common side effects include muscle twitches and mood changes

As soon as the effect of these substances wears off, the body begins to gradually return to its normal metabolic rate