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The concept of blocking the IGF1 receptor in cancer is based on sound experimental animal data showing that targeting this receptor results in tumour cell apoptosis, the principle therapeutic hurdle in cancer

The SURPASS phase III clinical trials for tirzepatide involve more than 13,000 patients with T2D and aim to gain a better understanding of its efficacy and safety (ClinicalTrials.gov Identifier: NCT04255433)

Side effects with 0.5 mgtypically mild nausea, constipation, or reduced appetiteare generally less pronounced than at higher doses because lower amounts of the medication are in your system