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The GLP-1 receptor antagonist, exendin-(9-39), has been used to demonstrate physiologic effects of endogenous GLP-1 in human studies

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Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and patients with type 2 diabetes using exendin [939] as a GLP-1 receptor antagonist