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In the future, this could lead to an expansion in the range of indications (clinical uses) that GLP-1RAs are licensed and used for

If you have not yet done this protocol, you will find this protocol is NOT EASY

The peptide mimetic DPP-4 inhibitors including vildagliptin, saxagliptin and teneligliptin, were identified by peptide-based substrate substitution experiments, while the non-peptide mimetic group such as sitagliptin, alogliptin and linagliptin, were derived from the inhibitor and initially found in random screening

Peptides, due to their complex amino acid sequences and inherently sensitive molecular architecture, are particularly vulnerable to environmental stressors