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SKU: 34311093073

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6,15 This review summarizes recent advances in the pathophysiology of DN, discusses current diagnostic and therapeutic strategies, and highlights potential future directions in managing this debilitating condition

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In addition, A1R signaling inhibits excitatory synaptic transmission through the inhibition of glutamate release, ionotropic glutamate receptors, and neuronal excitability via inward rectifying, cAMP/PKA/DARPP-32 pathway, as well as calcium-activated potassium channels (61, 62)