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Less common adverse effects have included pruritic rash, muscle weakness in uremic patients, and seizures in patients with seizure disorders

The company saw an impressive 56% year-over-year (YOY) boost to revenue, thanks in large part to $12.8 billion in combined sales of its two main GLP-1 agonists, Mounjaro and Zepbound

The doctor uses a needle to remove a small piece of liver tissue and looks at it in the lab

Kinetic fluorescence measurements were performed in a microplate reader at an excitation wavelength (ex) of 389 nm and an emission wavelength (em) of 513 nm, with a runtime of 15 min at 1-min intervals and a temperature set to 37 C to determine the average velocity (Vmean) of the enzymatic reaction