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Analysts have suggested that approval in CSU alone could make the drug a blockbuster, with sales of more than $1 billion a year, and Novartis is running phase 3 trials for chronic inducible urticaria (CINDU) and multiple sclerosis (MS), and phase 2 studies in hidradenitis suppurativa (HS) and food allergy indications

In addition, combination of NNMTi with exercise further increases systemic energy expenditure, accelerates fat breakdown, and enhances muscle strength and endurance

The proliferation of unauthorized manufacturers and online sellers can cause confusion among consumers, fuel market noise, and undermine trust in legitimate therapies