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The improvements in fasting food cravings and appetite score occurred in parallel to the reductions of five sub-scales of food craving (desire, anticipation of positive reinforcement, anticipation of negative reinforcement, lack of control, and hunger scores), and while cognitive restraint remained unchanged by tirzepatide treatment, participants reported reductions in disinhibition and perceived hunger

Conte Center Grant MH-094268, NIH Grants MH-084018, MH-105660, and MH-107730