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Though rare, allergic reactions can occur

Off-gassing from carpeting may cause mast cell release in the case of sick building syndrome.[ref] Sodium benzoate, a common preservative, causes histamine release in people with allergies and asthma.[ref] Aspirin and other salicylates can cause histamine problems for some people, possibly through basophil activation.[ref] Polysorbate 80, a common food additive, causes histamine release.[ref] Polysorbate 80 is in most brands of pickles except organic pickles

Chandler CJ, Wang TT, Halsted CH

They are generally much more accessible you can get them through telehealth pharmacies, med spas and theyre much cheaper than the brand version, NBC News medical contributor Dr