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171 GWAS in major populations consistently highlight urate transporter genes as pivotal loci influencing serum uric acid levels, 138,139 notably SLC2A9 (GLUT9) and SLC22A12 (URAT1), involved in urate reabsorption from urinary filtrates

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Gut and immune interface: BPC157 and KPV are investigated for GI mucosal protection and immune balance, allowing study of epithelial barrier integrity and cytokine modulation under injury or stress

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