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Patients with active hematologic disorders, those currently on erythropoietin therapy, or anyone with contraindications identified during consultation should discuss alternative approaches with their provider

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Lancet 376(9742):687697 Hurvitz SA et al (2018) Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial