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Common side effects for both: Nausea (most common, improves over time) Diarrhea or constipation Vomiting (less common) Abdominal pain or bloating Reduced appetite (this is intended, but can be extreme) Fatigue, especially in first month Managing GI side effects: Eat smaller, more frequent meals Avoid fatty, greasy, or spicy foods Stay hydrated Don't lie down immediately after eating Consider anti-nausea medication if severe Most side effects peak in weeks 2-4 of each new dose, then improve significantly

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Nature+2MDPI+2 When people talk about peptide therapy in clinics and on social media, they often mean both these well-validated, regulator-approved peptide drugs and a growing assortment of compounded or research peptides marketed for fat loss, musculoskeletal repair, sexual function, brain health and skin rejuvenation