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Month 01 (Weeks 04) What to expect: Weight loss is slow and steady Most patients lose 24 lbs in the first month Your body adjusts to the medication Appetite starts decreasing Cravings reduce, especially late-night or stress eating Some people notice better sleep and fewer sugar crashes This is the foundation month. Youre not supposed to drop weight rapidly yet
Aggressive force, rapid injection, or vigorous agitation can disrupt this structure through a process called mechanical denaturation
2025;26(1) doi: 10.1111/obr.13841
Starting doses are usually 300 mg daily, gradually increased
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