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Results Thirty-nine subjects completed the study (placebo, n = 19

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Mertens-Talcott SU, Bomser JA, Romero C, Talcott ST, Percival SS

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It indicated that liraglutide significantly reduced the risk of bone fractures (OR = 0.38, 95% CI 0.170.87), whereas exenatide increased the risk of bone fractures (OR = 2.09, 95% CI 1.034.21), compared to placebo or other antidiabetic drugs

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Western blot analysis showed that MOR protein levels were significantly reduced in PVN Glu neurons of mice injected with AAV-DIO-shMOR-EGFP compared to AAV-DIO-EGFP-infected controls, validating the efficacy of MOR knockdown (Fig

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