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They are new drugs - which mimic GLP-1, a natural hormone that regulates hunger - and the potential side effects from using them in the long term are only just beginning to emerge

It also notes age eligibility varies by state, with most requiring 18 or older and some restricting to 21 or older, and that some states authorize semaglutide first while requiring step therapy before tirzepatide is approved

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Future research is expected to expand on this paradigm through the development of triple agonists targeting additional metabolic pathways, exploration of oral and long acting formulations, and refinement of patient selection criteria to maximize clinical benefit while minimizing risk