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These mainly involve the inhibition of the master regulator MITF, resulting from the reduction of intracellular cAMP levels, increases in cytoplasmic -catenin and/or the activation of ERK signaling
doi: 10.3389/fmicb.2026.1705784 Received 16 September 2025 Revised 23 January 2026 Accepted 05 March 2026 Published 26 March 2026 Volume 17 - 2026 Edited by Magorzata Anna Mar, University Hospital La Paz Research Institute (IdiPAZ), Spain Reviewed by Shanshan Huang, Fudan University, China Changwei Yang, Fujian Medical University, China Jiale Chen, Chengdu University of Traditional Chinese Medicine, China Updates Copyright 2026 Qi, Kang, Li, Wang, Lin, Zhan, Zeng, Xiao, Liu, Chen and Liu
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