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Some studies suggest possible improvements in sleep latency (how quickly people fall asleep), sleep efficiency, or sleep-wake function, but no large modern insomnia RCTs or meta-analyses were identified [47]

7-Keto DHEA 5,6 7-Keto-DHEA is believed to enhance thermogenesis (heat production) and basal metabolic rate by modulating the activity of 3 key metabolic enzymes, including: Glycerol-3-phosphate dehydrogenase, cytosolic malic enzyme, citrate lyase

Fomina M, Hillier S, Charnock JM, Melville K, Alexander IJ, Gadd GM

Of note, whereas drug adverse effects may emerge early because of the sudden exposure of the body to a new substance, adverse effects tend to be clearly present only when a critical threshold, usually related to blood level, is reached