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Severe abdominal pain, especially if its sharp or radiating to your back, also needs urgent evaluation

Furthermore, LS has been proven to have antioxidant properties in a rat model of diabetic nephropathy produced by streptozotocin, as demonstrated by a decrease in renal MDA levels and an increase in renal SOD, catalase, and GSH levels 60

Non-GLP-1 alternatives like metformin, topiramate, bupropion-naltrexone, and zonisamide may also be used, either alone or in combination, depending on your needs

Sarah Fishman, M.D., a professor of medicine, endocrinology, diabetes, and bone disease at Icahn School of Medicine at Mount Sinai in New York City