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A preliminary evaluation of this food supplement involved 78-subjects (21 males and 57 females), aged 42.5 years for men and 39.8 years for women, that were supplemented with one stick pack of food supplement daily for one month (containing pomegranate extract 500 mg, ascorbic acid 200 mg, niacin 16 mg, riboflavin 7 mg, pantothenic acid 6 mg, thiamine 5.5 mg, pyridoxine 4 mg, folic acid 200 g, biotin 50 g, cobalamin 12.5 g)

For severe nausea, antiemetic medications may be prescribed, though this should be discussed with the healthcare provider