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Administering 200 mg/kg curcumin to male SpragueDawley rats with autistic features has decreased the release of TNF-, oxidative stress, degradation of matrix metalloproteinases, and mitochondrial dysfunction

Int J Biomed Pharm Sci 2(2):7983 Domnguez-Oliva A, Hernndez-valos I, Martnez-Burnes J, Olmos-Hernndez A, Verduzco-Mendoza A, Mota-Rojas D (2023) The importance of animal models in biomedical research: current insights and applications

In some cases, it may introduce additional variables that have not been evaluated for safety, quality, or consistency

JaiswalM,MartinCL,BrownMBetal.Effects of exenatide on measures of diabetic neuropathy in subjects with type 2 diabetes: results from an 18-month proof-of-concept open-label randomized study.J Diabetes Complications.2015Nov-Dec;29(8):1287-94