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Back Drucker, DJ, Holst, JJ (28 March 2023) 'The expanding incretin universe: from basic biology to clinical translation', Diabetologia , 66, 1765-29

avoid storing in the door where temperature fluctuations are greatest Protect from light Keep pens in their original packaging until ready for first use Check expiry dates Use the earliest expiry date first and never use medication past its expiration Avoid temperature extremes Do not store near cooling elements or in areas where temperature may drop below 2C Product-specific room temperature allowances before first use: Trulicity (dulaglutide): May be kept at temperatures up to 30C for up to 14 days before use Wegovy (semaglutide): May be kept at temperatures below 30C for up to 28 days before use Bydureon (exenatide prolonged-release): May be kept at temperatures up to 30C for up to 4 weeks before use When collecting your prescription from the pharmacy, GLP-1 medications should be transported home promptly and refrigerated immediately

The World Health Organization on Monday released new guidance on GLP-1 medications for adults with obesity, recommending their long-term, continuous use when clinically appropriate

The biggest consideration is the dose, which is very high