These included the phospholipid precursor PA(22:1(13Z)/19:2(10Z,13Z)), the free fatty acid Ricinoleic acid (5.1-fold), the oxidative stress marker 7-Oxo-11-dodecenoic acid, and monoacylglycerols, most notably MG(20:3(6,8,11)-OH(5)/0:0/0:0), which increased dramatically by 15.6-fold
22 The relationship between insulin resistance and MASLD has not been fully elucidated, but potential mechanisms that promote MASLD/MASH include influencing hepatic lipid synthesis and catabolism, as well as impairing mitochondrial fatty acid -oxidation function
Mgliche Nebenwirkungen bei sehr hohen Dosen (ber 3 g tglich) knnen sein: Magen-Darm-Beschwerden (z
Tibbitt MW, Anseth KS (2009) Hydrogels as extracellular matrix mimics for 3D cell culture