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This schematic illustrates (left) the mechanism of action of edrophonium as a short-acting, reversible acetylcholinesterase (AChE) inhibitor that prevents acetylcholine breakdown at the neuromuscular junction

Metabolic profiling studies did not reveal an obvious metabolic explanation for the results, although markedly lower levels of one of hydroxylated metabolites (3-hydroxyacetyl- para -aminophenol