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J Int Soc Sports Nutr 10(1):6 Li N, Chen S, He Y, Chen Y, Duan X, He W et al (2025) Effects of oral supplementation of beta -hydroxy-beta -methylbutyrate on muscle mass and strength in individuals over the age of 50: a meta-analysis

It is the only isoform that is expressed exclusively in skeletal muscle, cardiac muscle, and fat cells and is regulated by insulin

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