Diet-induced obese (DIO) C57BL/6 J male mice were purchased from Jackson Laboratory (#380050, Bar Harbor, ME) at 16 weeks of age
Compounded Semaglutide is a customized version of the FDA-approved Semaglutide - the active ingredient in leading weight loss medications
This is underscored by the results of a clinical trial comparing the development of obese adults who received either semaglutide or liraglutide in addition to nutritional advice and physical activity, and significantly greater weight loss was achieved in the semaglutide group [102]
Toxicol Sci 85:809822 Roderburg C, Benz F, Vargas Cardenas D, Koch A, Janssen J, Vucur M, Gautheron J, Schneider AT, Koppe C, Kreggenwinkel K, Zimmermann HW, Luedde M, Trautwein C, Tacke F, Luedde T (2015) Elevated miR-122 serum levels are an independent marker of liver injury in inflammatory diseases