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2001 Mar 8;344(10):710-9

The high level of GSH in the antigen-presenting cells correlates with the increased production of IL-12 favoring Th1 response [68], and probably reduces the disulfide bonds of an antigen, which is a crucial step of antigen processing

In the model proposed by Lee, homocysteine is shunted away from the methionine synthesis pathway and toward the GSH synthesis pathway, creating a relative deficiency of methyl donors in order to keep up with increased demand for the glutathione needed for POP conjugation ( Fig 3 )

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