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Compared with the rapid translocation of Nrf2 induced by DEM, NFT treatment resulted in a rather slow, but constant rise in the intensity of nuclear Nrf2 signals (Fig

818 Ferroptosis in renal ischemia-reperfusion injury The kidney is extremely sensitive to I/R injury, and the mismatch between oxygen supply and oxygen demand leads to decreased oxidative metabolism, resulting in progressive damage of renal tubular epithelial cells