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Description

A signal-off fluorescent strategy for deferasirox effective detection using carbon Dots as probe and Cu 2+ as medium

Computational and Structural Biotechnology Journal

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The unique feature of this vector is that the amino acid substitution ( AT 87 Q ) allows for high performance liquid chromatography (HPLC) monitoring of the transgene globin levels in the patients cells (Ribeil et al., 2017), with further undergoing studies (ClinicalTrials.gov Identifier: NCT02140554, NCT03282656)