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Am Fam Physician 102:627628 Gerstein HC, Colhoun HM, Dagenais GR, et al (2019) Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial

Reverse Titration Method Weaning off GLP-1 medications can be managed through reverse titration, where the dosage is gradually reduced in the reverse order of the initial titration schedule

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This shift in microbial composition leads to an elevation of Lipopolysaccharide (LPS)