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In Section Effects of polymorphisms in glucoronosyl transferases we showed that polymorphisms in the glucoronosyl transferase enzymes can have a large effect on the amount of liver damage caused by moderate overdoses of APAP
Beyond protection, it also plays a critical role in the detoxification process
Crucially, FOXO4 knockdown significantly reduced the viability of senescent TM3 Leydig cells and substantially increased their rate of apoptosis
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