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Metformin has long been a top choice for the first drug to be tried if dietary and lifestyle changes are not sufficient to regain glucose control and metabolic health

Angiotensin-(1-7) attenuates the anxiety and depression-like behaviors in transgenic rats with low brain angiotensinogen

In the same way, dopamine-loaded albumin/PLGA polymeric nanoparticles in the 300400 nm size range were effectively targeted to brain and restored motor function in a mice model of PD [60]